Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonists. These drugs work by mimicking
incretin, a natural hormone that stimulates insulin release, helping to regulate blood sugar.
Tirzepatide, like semaglutide, belongs to the class of drugs known glucagon-like peptide-1 (GLP-1)
receptor agonists. What sets tirzepatide apart is its unique mechanism of action: it activates both
glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors,
two receptors that play key roles in regulating blood sugar levels.
Compounded semaglutide and tirzepatide are both primarily prescribed for for weight management and
diabetes. Clinical trials have proven that semaglutide and tirzepatide are both effective in weight
management when combined with a proper diet and exercise plan. It works by regulating blood sugar
and digestion, curbing appetite, slowing the rate at which the stomach empties, and increasing feelings
of fullness after meals. These effects collectively reduce total caloric intake, which is crucial for weight
management. These medications have also been shown to reduce heart-related risks in obese patients
as well.
Semaglutide and tirzepatide can cause side effects. The most common are gastrointestinal symptoms,
including nausea, vomiting, diarrhea, abdominal pain and constipation. In some cases, more severe side
effects may occur, such as pancreatic inflammation, vision changes or low blood sugar, especially when
taken with other diabetes medications.
Individuals with a personal or family history of medullary thyroid carcinoma.Those with Multiple
Endocrine Neoplasia syndrome type 2. Patients with a history of severe gastrointestinal disease,
including gastroparesis, as these medications can slow gastric emptying. People under 18 years of age,
as its safety and efficacy in pediatric patients have not been established.
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